The company will carry out both refurbishment and new build works for Dewsbury and District Hospital.
Works include a new main entrance to provide a central focal point for patients, visitors and staff.
Kier will complete the work in two phases, starting later this year by relocating services into the Ridings building and Service Centre.
Phase two will involve developing the new main entrance.
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Kevin Oxley, MYHT Director responsible for capital project developments, said: "We are delighted to announce the appointment of Kier as our P21+ partner for the Dewsbury Hospital redevelopment.
"Kier have a long and distinguished track record in both hospital redevelopment and new builds. We look forward to them bringing their experience and expertise to this important project."
The contract was awarded under the three year ProCure 21+ framework along with four other healthcare projects.
Altogether, the five contracts are worth £247 million.
Robbie Blackhurst, Kier's framework manager, said: "We are pleased to have been chosen to deliver this exciting reconfiguration of Dewsbury and District Hospital, which will help to provide a more streamlined service for patients.
"Kier has extensive experience in the provision of healthcare schemes, having secured over 50 projects through the P21+ framework in the past four years, and we’re looking forward to working closely with MYHT’s clinical stakeholders to design and deliver this transformational programme."
(LM/CD)
