The work to install new netting to the station's glass roof is to commence on Saturday, 15 June.
The current station netting was installed 25 years ago and is starting to show some signs of wear and tear.
The work will continue until October and is being carried out in phases to reduce the impact on passengers.
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However, some platforms will be closed and trains will be diverted to alternative platforms.
Engineers will use raised platforms and rope systems to safely access the station roof and install the new netting.
Passengers are advised to check before they travel as there may be some disruption.
Kara Wood, acting route strategy director for Network Rail's North West route said: "We are doing this work in phases so we can keep the station open to passengers.
"While some platforms will be closed as we install new netting, the majority of the station will be unaffected. Passengers should check www.nationalrail.co.uk before they travel."
